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Janssen Biotech, Inc., formerly Centocor Biotech, Inc., is a biotechnology company that was founded in Philadelphia in 1979 with an initial goal of developing new diagnostic assays using monoclonal antibody technology. ==History== In 1982 Centocor transitioned into a publicly traded company. Subsequently, the company moved to a larger facility in Malvern, Pennsylvania (a northwest suburb of Philadelphia). In 1984, Centocor opened an overseas plant in Leiden, the Netherlands. In 1997, eighteen years after its foundation, Centocor achieved its first year of operating profitability. In 1998, Centocor sold its diagnostic division to Fujirebio, Inc..〔(Centocor reaches agreement to sell oncology diagnostics business ), 1998 press release〕 In 1999, Centocor became a wholly owned subsidiary of Johnson & Johnson, the worldwide manufacturer and marketer of healthcare products. Since being acquired by Johnson and Johnson, Centocor has increased its annual sales from approximately $500 million to more than $2 billion. During the same period, research and development investment increased from $75 million to more than $300 million. In 2004 Centocor purchased a new manufacturing plant in St. Louis, Missouri, and is currently opening a new manufacturing facility in County Cork, Ireland. The Dutch plant has been expanded substantially with a $250 million investment in additional production facilities, which were opened in 2006. In 2007, Centocor broke new ground in advertising by releasing Innerstate, believed to be the first theatrically released documentary film both created and entirely funded by a drug company, to promote Remicade (Infliximab).〔Stephanie Saul. "Drug Gets a Cameo in a Film Backed by Its Maker", New York Times, February 21, 2007. http://www.nytimes.com/2007/02/21/business/media/21adco.html〕 In 2008, Centocor, Inc. and Ortho Biotech Inc. merged to form Centocor Ortho Biotech Inc. In June 2010 Centocor Ortho Biotech acquired RespiVert, a privately held drug discovery company focused on developing small-molecule, inhaled therapies for the treatment of pulmonary diseases.〔(Centocor Ortho Biotech Acquires RespiVert ) News article from InfoGrok.〕 In June 2011 Centocor Ortho Biotech changed its name to Janssen Biotech, Inc. as part of a global effort to unite the Janssen Pharmaceutical Companies around the world under a common identity. In December 2014, the company announced it would co-develop MacroGenics cancer drug candidate (MGD011) which targets both CD19 and CD3 proteins in treating B-cell malignant tumours. This could net MacroGenics up to $700 million.〔http://www.genengnews.com/gen-news-highlights/janssen-joins-macrogenics-in-up-to-700m-cancer-collaboration/81250728/〕 In January 2015, the company announced it will utilise Isis Pharmaceuticals' Rna-targeting technology to discover and develop antisense drugs targeting autoimmune disorders of the gastrointestinal tract, with the partnership potentially generating up to $835 million for Isis.〔http://www.genengnews.com/gen-news-highlights/janssen-isis-pharma-ink-up-to-835m-antisense-agreement/81250763/〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Janssen Biotech」の詳細全文を読む スポンサード リンク
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